Job Description

Senior Principal Stem Cell Research Scientist, Endocrinology

Job Description

The Senior Principal Research Scientist is self-reliant with a proven record of accomplishments, both leading others in a matrix environment and independently identifying and solving complex problems using sophisticated scientific methods and analytical thought across a number of critical and diverse projects. This position reports to the Distinguished Fellow in charge of the Cell and Gene Therapy Research Discovery Team. The successful candidate is regarded as an emerging expert in a field of research, specifically with expertise in the molecular and cellular biology of endocrinology, and will provide valuable advice to other research project teams on a regular basis. They must develop research approaches and medical strategies that inform potential clinical approaches.

Key Responsibilities

• Designs and performs sophisticated, technically challenging experiments that impact the achievement of department and critical T1D program goals.
• Provides input and contributes to global therapeutic area strategic imperatives.
• Contributes toward medical interpretation of data for the assigned product(s).
• Generates effective hypotheses and encourages new experimental approaches or data analysis methods.
• Draws datadriven conclusions and identifies comprehensive implications for findings.
• Develops novel and creative solutions using specialized depth in scientific discipline to overcome obstacles; may advise other team members.
• Performs advanced experimental troubleshooting, methods development, and mentors other team members on projects outside their own.
• Supports development of study protocols, lifecycle management plans, and other key study documents in conjunction with other line functions.
• Makes substantive contributions that impact critical project activities and scientific strategies within discipline.
• Imports new principles or concepts from other fields to establish new progress.
• Supports strategic alignment of program/product, working crossfunctionally and partnering with other key functions.
• Provides medical input and guidance to early access programs and individual IND (early access) requests; may participate and support the preparation of regulatory documents.
• May generate external peerreviewed materials.
• Provides indepth technical advice and develops theoretical premise for issues within own area.
• Performs other duties as assigned.

Required Knowledge and Skills

• Specialized depth of knowledge in endocrinology and methods to enable T1D novel scientific research.
• Consistently advises or mentors others to execute technically challenging, complex experiments that directly impact projects and programs within discipline.
• Consistently identifies and leverages new, productive approaches in experiments.
• Demonstrated initiative and ability to impact and advance projects through scientific creativity and insights.
• Assigned to the more challenging or highervalue project tasks/problems.
• Demonstrated determination and persistence in supporting projects.
• Strong communication skills with the ability to write advanced technical documents and persuade others presenting technical/scientific concepts to diverse audiences.
• Values teamwork and collaboration to solve problems and design strategies.

Education and Experience

• PhD in cell biology, biochemistry, endocrinology, or related disciplines with 6 years of experience in analysis of research data and publications.
• MD (Preferred).

Pay Range

$169,600 - $254,300

Disclosure Statement

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other jobrelated factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive marketleading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off, educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation

OnSite Designated

Flex Eligibility Status

In this OnSite designated role, you will work five days per week onsite with ad hoc flexibility. Note: The Flex status for this position is subject to Vertexs policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation and is committed to equal employment opportunity and nondiscrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an EVerify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com.

Seniority Level

MidSenior level

Employment Type

Fulltime

Job Function

Engineering and Information Technology

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